There was quite a bit written earlier in the year about the Mpack threat, I even managed a little piece myself! Symantec recently added an update to their analysis of Mpack. It’s not really good news I’m afraid.
They have listed the exploits that are targeted by Mpack, and Eric Larkin of PC world went one further and asked Symantec what we need to do to make sure that we are not vulnerable.
See his article at the PCWorld Blog for a list of Must Close Holes, and remember to keep all your software up to date. If you aren’t too sure how to check your software then Secunia Software Inspector is a great tool that will help you out here.